Introduction of Medicinal Chemistry & Heterocyclic Compounds
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Nano-Ceria (CeO2): An Efficient Catalyst for the Multi-Component Synthesis of a Variety of Key Medicinal Heterocyclic Compounds
This review gives an overview of the applications of ceria nanoparticles as inexpensive, efficient, reusable, and environmentally sustainable heterogeneous catalysts for the synthesis of a variety of key medicinal heterocyclic compounds with the emphasis on mechanistic aspects of the reactions. Literature has been surveyed from 2005 to 2018.
متن کاملSynthesis of Medicinally Privileged Heterocycles through Dielectric Heating.
BACKGROUND Heterocyclic compounds are intriguing part of modern drug discovery research. Ecofriendly syntheses of heterocycles, following green techniques, are privileged routes to protect Mother nature. Microwave-assisted synthesis of chemical compounds is considered as a major greener pathway, both in academia and industry. METHODS A total of 106 publications (including a few authentic web ...
متن کاملSynthesis, Evaluation of Anticancer Activity and QSAR Study of Heterocyclic Esters of Caffeic Acid
Caffeic acid phenethyl ester(CAPE) suppresses the growth of transformed cells such as human breast cancer cells, hepatocarcinoma , myeloid leukemia, colorectal cancer cells, fibrosarcoma, glioma and melanoma. A group of heterocyclic esters of caffeic acid was synthesized using Mitsunobu reaction and the esters were subjected to further structural modification by electrooxidation of the catecho...
متن کاملAntibacterial Studies of Dihydropyrimidinones and Pyrimidinethiones
Heterocyclic compounds containing nitrogen are promising structure moiety for drug design. Dihydropyrimidines are one of the important heterocyclic compounds, which are of interest due to its efficiency towards various pharmacological uses. These are large group of structurally diverse compounds which are known to possess some characteristic properties like manifestations of novel structures, t...
متن کاملThiadiazole Analogs as Potential Pharmacological Agents: a Brief Review
Recently, heterocyclic compounds analogues and their derivatives have attracted strong interest in medicinal chemistry due to their biological and pharmacological properties. The small and simple thiadiazole nucleus possesses numerous biological properties like antitumor, antimicrobial, anti-inflammatory, anticonvulsant, and antidiabetic activities. These activities are also possessed by its su...
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